As the first-to-market solution focusing on cryo cassette storage and sample management, CryoArc Tera for Cassettes protects your high-value CGT products, securing critical quality attributes in the final product.
CryoArc Tera for Cassettes is essential for CGT development, technology transfer, and manufacturing workflows as it holds up to 990 cassettes in any combination of 25 mL, 50 mL, or 250 mL volumes. Its robust, documented sample integrity protection along with user-friendly sample management and control ease your manufacturing workflows and support your cold chain strategies.
A familiar high-efficiency LN2 stainless steel freezer is the foundation of Tera for Cassettes. It also includes an insulating sample transport robotic tower, and powerfully intuitive CryoArc Software. Together, these combined components boost efficiency and scalability in your automated cell and biological sample management workflows.
The Sample Experience
Each sample storage cassette is individually loaded into the insulated robotic tower and then automatically delivered to user specified or system optimized locations within the CryoArc Tera for Cassettes. Inventory information is tracked at the cassette level, and may be shared with your facility’s LIMS.
The liquid nitrogen vapor phase provides a consistent -190 ºC temperature for stored samples from top to bottom. In case of electrical outages, LN2 interruption, or other unforeseen hazards, The Tera for Cassettes cryogenic freezer provides amazing longevity, with up to 21 days of temperature stability to protect your product from harm. An onboard uninterruptable power supply (UPS) ensures all samples are safely stored in the event of power disruption, maintaining the storage environment and data integrity.
Targeted and non-targeted samples are protected from warming above Tg (glass transition temperature) both in storage and during retrieval by the insulated robotic tower and intelligent software controls.
One cassette is retrieved at a time to protect innocent samples, and every exposure is controlled and traced to ensure that product always remains below the critical temperature.
Optional CryoPod Carriers attach to the Tera for Cassette’s rim to hold samples when they are removed from the sample transport robotic tower. These award winning cryo carriers maintain sample environment temperatures at less than -150ºC for over 3 hours, depending on fill level, heat load, and lid placement. This maintains confidence in sample potency when transporting frozen cassettes or preparing to use samples at a workstation. Temperature, date, and time are logged, and users are alerted if temperature ranges are breached.
The User Experience
CryoArc Tera for Cassette’s no-hassle sample placement and retrieval process and ergonomic vending machine styled design protects users from the physical stress and strain of leaning over a storage tank and also helps to minimize personal protective equipment requirements.
A friendly touchscreen graphical user interface empowers users of any skill level to effortlessly manage detailed cell therapy product inventory and rapidly execute orders. User permission levels prevent accidental sample access while empowering diligent record-keeping, enabling the Tera for Cassettes to become a shared resource
The Data Experience
CryoArc software uses an optional WebAPI module to seamlessly integrate with any homegrown or enterprise LIMS. In addition to smooth data flow, CryoArc Tera for Cassettes supports adherence to FDA 21 CFR, Part 11 requirements to satisfy regulatory demands, if required. All sample, chain-of-custody, and performance data may be downloaded in a standardized format for inclusion in audit reports.
Key Features
Easily Control and Manage the Details
Cryo critical software platforms from Azenta are vital to your cold chain management strategy.
Integrated CryoArc Software:
- Tracks individual sample location, sample movement, and user access over the sample’s lifetime
- Captures real-time environmental data including temperature, unexpected events, alarms, LN2 usage, and LN2 levels
- Supports 21 CFR Part 11 compliance
- Optional library management allows users to partition the storage space and assign access privileges to individual or groups of users
- Optional alerts management enables custom alert configurations and notifications via email or mobile devices in response to system behavior
Remote Monitoring Portal
- Simplifies cryo freezer maintenance across your lab or enterprise
- Empowers real-time cryogenic storage system monitoring at any time and from anywhere in the world
- Communicates critical at-a-glance metrics with text or email alerts if conditions change
FreezerPro Inventory Management
- Facilitates inventory tracking, robust reporting, detailed searches, and audit trails
- Seamlessly integrates with CryoArc Software, along with other Azenta automated storage systems and devices to enhance cold chain management convenience
- Supports 21 CFR Part 11 compliance along with Parts 21, 58, 210, cGLP/cGMP, and Section 508 accessibility guidelines
- Offers high security with remote access
- Scales to dynamic manufacturing demands
Scale and Change at Your Pace
As a market-leading automated cryogenic storage system and first-to-market high-volume cassette solution, CryoArc Tera for Cassettes easily adapts to your lab’s size and changing needs.
- Accepts any combination of 25ml, 50 ml, and 250ml cryo cassettes
- Single interface and familiar software when adding multiple units – including our small-collection CryoArc Pico, medium-collection CryoArc Deca, and large-repository CryoArc Tera models – to your lab or enterprise
- Efficient space use and rapid system integration
Round out your workflows with additional high-performing Azenta cryogenic tools:
Extend Cryogenic Storage Confidence
- Flexible Support Plans keep your CryoArc Tera for Cassettes investment running at peak performance
- Trainings develop your team’s skillsets with applicable knowledge
- Qualification Services (IQ/OQ/PQ) help you achieve compliance requirements
- Equipment Repair, Refurbishment, or Relocation on request
