Sample Management Redefined: Bridging Laboratory Precision with Remote Frontiers As a pioneer in sample management solutions, Azenta is on a mission to streamline and revolutionize the way samples are handled, stored, transported, and managed. Our comprehensive portfolio of services has significantly expanded with the integration of B Medical advanced storage solutions, which have proven instrumental […]
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The structure of mRNA has been known for decades, but only in recent years have researchers unlocked its potential for therapeutic development. With the right delivery vehicle, mRNA products can replace defective proteins in the cell, generate antigens for immunization (e.g., COVID vaccines), or edit the genome via CRISPR technology. Let’s review the structural features of a […]
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With the emergence of cell and gene therapy and other gene editing technologies, interest in efficient and effective gene delivery systems has surged in recent years. Commonly used systems include adeno-associated viruses (AAV) and lentiviruses. While both are effective transfer vehicles, there are key differences in how they infect cells and deliver their genetic payload. Most notably, lentiviruses […]
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Basics of Synthetic DNA and Gene Synthesis Artificial DNA synthesis, a fundamental tool of synthetic biology, enables scientists to create DNA molecules of virtually any sequence without a template. Construction begins with the base-by-base synthesis of oligonucleotides (oligos), followed by assembly into double-stranded DNA (dsDNA) fragments. These custom DNA fragments can be used directly, cloned […]
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Vaccines are some of the most valuable biological materials that clinicians produce and use. They help prevent health issues for millions each year. However, much of the vaccines lost are due to degradation that occurs when they warm during vaccine transport. Extreme weather, natural disasters, and other emergencies can put laboratories at risk and can […]
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