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BioStore™ -190°C LN2-Based Automated Storage System Integrates with Cytiva's Chronicle™ Automation Software

Why Integrate

Sample traceability, process control and monitoring through integration with Chronicle™ automation software from Cytiva

Combining the BioStore -190°C LN2-Based Automated Storage System and Chronicle™ Automation Software from Cytiva provides users with long term cryogenic storage for biologic samples and product at -190°C whilst truly leveraging the automation of process development and manufacturing for cellular products.

In the words of Linda De Jesus, Vice President and Chief Commercial Officer, Azenta Life Sciences, "By integrating a freezer platform like the BioStore -190°C LN2-Based Automated Storage System with Cytiva’s Chronicle software, we are helping customers add the documented rigor around cold chain, inventory and handling which previously did not exist. This integrated solution will allow customers to expand the role of automation in their workflows and documentation to help bring products to the market faster."

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BioStore & Chronicle

BioStore III Cryo

 

 

 

BioStore -190°C LN2-Based Automated Storage System from Azenta Life Sciences

BioStore provides best in class automated -190°C storage for cellular products and other materials requiring storage temperatures below glass transition (Tg). Quality is assured by viewing user access, sample inventory, history, and audit-trail reports.

There are two main areas where the BioStore -190°C LN2-Based Automated Storage System benefits cellular product customers: process control and product integrity.

 

  • Optimized cold chain handling and documentation; execute consistent, repeatable inventory cold chain SOPs while limiting untracked transient warming exposures for stored materials, regardless of user training and experience
  • Proprietary control software, records all system user logins, consistently executing and documenting every inventory interaction. Inventory records are updated in real-time, featuring 19 available reports, and supports 21-CFR-11 compliance
  • Scalability is easy, added systems will apply the same collection management standards across sites, ensuring consistent ordering processes
  • Maintains stable freezer temperatures during material storage and retrieval activities to protect sample integrity
  • 75% faster order processing times v manual methods, with better accuracy and quality
  • Rack lifting system, slows warming of non-targeted samples in the insulating tower by 70% compared with ambient exposure
  • Best in class risk mitigation for high-value materials requiring storage temperatures below glass transition (Tg); with temperature hold time of up to 23 days in the event of a natural disaster or other emergencies

 

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Chronicle Software

 

 

 

Chronicle™ Automation Software from Cytiva

Chronicle™ is a fit-for-purpose solution designed to optimize complex cell therapy process development and manufacturing. It provides real time supply chain tracking, hardware performance monitoring, SMS or email alarms, and comprehensive electronic batch records. Built by platform solution engineers, Chronicle™ integrates with a variety of third-party instruments and has been independently audited against GAMP5, 21-CFR-11, and EU Annex 11.

 

  • Electronic batch records: implement electronic batch records that comply with regulatory requirements
  • Release by exception: review deviations efficiently with automated workflows to support release by exception
  • eSOP operator support: save operator time and reduce mistakes with electronic SOPs that adapt to changing conditions, perform calculations, and integrate instrument data
  • Instrument monitoring: monitor all connected instruments from inside or outside the cleanroom with real-time lab dashboards, email and SMS alerts
  • Barcode traceability: trace your products and consumables with stock control, barcode label printing, and scanning
  • Maintenance control: manage service records for all your instruments with full history, document management, and automated preventive maintenance notifications
  • Manage capacity: synchronize multiple VIA Freeze™ controls to start at the same time for larger volumes
  • Seamless connectivity: application programming interface (API) enhances interoperability with GE Healthcare Life Sciences and 3rd party devices

 

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Azenta Life Sciences & Cytiva

Azenta Life Sciences logo

 

About Azenta Life Sciences

Azenta Life Sciences, formerly a division of Brooks Automation (Nasdaq: BRKS) is a leading provider of life science sample-based solutions. As a service provider to labs around the world, Azenta Life Sciences offers a full suite of reliable cold-chain sample management solutions and genomic services across areas such as drug development, clinical research and advanced cell therapies for the industry's top pharmaceutical, biotech, academic and healthcare institutions globally

Azenta Life Sciences' GENEWIZ division is a leading provider of DNA gene sequencing and gene synthesis services.

The organization is headquartered in Chelmsford, MA, with operations in North America, Europe and Asia.

Cytiva

 

 

 

About Cytiva

Cytiva is a global life sciences leader with more than 7,000 associates across 40 countries dedicated to advancing and accelerating therapeutics.

As a trusted partner to customers that range in scale and scope, Cytiva brings speed, efficiency and capacity to research and manufacturing workflows, enabling the development, manufacture and delivery of transformative medicines to patients.

 

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Resources

BioStore™ LN2-Based Automated Storage System Software Controller

BioStore™ LN2-Based Automated Storage System Software Controller

Videos
BioStore™ -190°C LN2-Based Automated Storage System User Safety

BioStore™ -190°C LN2-Based Automated Storage System: User Safety

Videos
BioStore™ -190°C LN2-Based Automated Storage System - Intuitive Software Interface Flyer

BioStore™ -190°C LN2-Based Automated Storage System - Intuitive Software Interface Flyer

Brochures & Sell Sheets
CryoPod™ and Filling Station Flyer

CryoPod™ and Filling Station Flyer

Brochures & Sell Sheets
Cryopreservation Best Practices for CAR-T Cell Storage

Cryopreservation Best Practices for CAR-T Cell Storage

Whitepapers & eBooks
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